This is the story of Upma Dubey, a 37 year old lady who had undergone IVF at other prominent infertility clinics for 4 times resulting in failure on every attempt. Due to repeated loss, the couple was in a state of high anxiety. This affected Upma’s sleep since she realized that her husband Pawan was getting depressed. They were caught between the prevailing circumstance and their desperate desire of becoming parents.
While they were at this miserable condition, GENOME showed them a ray of hope. After receiving an enquiry from them, we immediately fixed an appointment for medical counselling and examination at our centre at Raipur.
On Upma’s visit, she informed about her hysterolaparoscopy which she has undergone on 20th December 2016. After going through her medical history and examining her, our reproductive medicine specialists came to know that Upma had IVF failures due to low AMH which resulted in unsuccessful implantation.
On further diagnosis through hysteroscopy (a process to examine the cervix and the inside of uterus), our specialists also deducted that she had vesicular type lesion on the left lateral wall of her uterus.
What is low AMH?
AMH or Anti-Mullerian Hormone is released by the granulosa cells present in ovarian follicles. Initially it is produced in primary follicles and this stage is termed as primordial follicle. In this stage, the follicles are so microscopic that they cannot even be noticed by ultrasound.
Low AMH- What does it indicates?
Low AMH results usually coincide with high FSH or Follicle Stimulating Hormone results, and when this happens, it indicates a low ovarian reserve. FSH is produced by the brain which in turn supports the development of follicles in the ovaries.
What causes low AMH?
Causes of Low Ovarian Reserve. It is a premature reduction in the number of eggs which may occur due to chromosomal anomalies such as Turner Syndrome (where the female does not have two X chromosomes, or genetic abnormalities like Fragile X).
What is vesicular lesion?
It is a kind of mucocutaneous disease that occurs when both vesicles and bullae i.e. blisters form fluid-filled lesions and grow on the wall of any organ.
After analysing Upma’s health, we decided to treat her low AMH levels first so that her body becomes healthy for a successful implantation. This was followed by the treatment of vesicular lesion that was diagnosed at the left hand side of the lateral wall.
At the initial stage before the final treatment for implantation, she was treated with the help of antibiotics so that her body gets perfectly ready for processes further.
Upma & Pawan’s Journey through IVF @Genome
Our team at Genome Raipur Centre decided that the best treatment for Upma’s pregnancy was In-Vitro Fertilization or IVF. It is the most popular and successful Assisted Reproductive Technology procedure which involves the fusion of sperm and ovum cultured in a laboratory dish. In simpler terms, the fertilization takes place outside of the human body.
Upma’s treatment was done through ESD i.e. Egg Sharing Donor followed by ICSI i.e. Intra-Cytoplasmic Sperm Injection by utilizing her husband’s sperm.
During their journey through IVF, Pawan put complete faith and reliance on our team adding that “The doctors at Genome are very supporting. Even after continuous failures of repeated IVF treatments we had earlier, they tried to comfort our agitated minds and motivated us to try once more. Starting from the doctors to the nurses, everyone at Genome made our journey through IVF an unforgettable one.”
Hope, Patience & Success
A few months later, Upma and Pawan were glad to conceive their first ever baby.
“I was fortunate that my husband brought me here and today I am pregnant in the first cycle itself. Team Genome helped us overcome all the challenges and thus, helped us fulfil our dream,” said a jubilant Upma. Upma and Pawan are the proud parents of twins born through IVF done at Genome – The Fertility Centre in Raipur.
At Genome, we are glad to gift parenthood to couples who are challenged by nature yet brave enough to challenge and change their destiny!